Here's a demonstration where I got to borrow 2 killer guitars.
It's the Paul Reed Smith John Mayer silver sky signature guitar, versus a pristine 1965 fender Strat from Norms Rare Guitars. The John Mayer silver sky sells for a little over $2000 and the 65 fender Stratocaster is priced at $21,000.
I did not change the amplifier settings when I switched guitars. The entire performance is played through my Naylor Superdrive 60 head and a Marshall 412 cabinet.
After the performance Aidan Scrivens and I talked for a few minutes about the virtues of both guitars. We fell in love with both of them!